Cholesterol metabolism: Video, Causes, & Meaning | Osmosis
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This podcast summarizes the 4 major cellular uses of cholesterol, its biosynthesis, and the regulation of the rate-limiting enzyme HMG CoA reductase by intracellular cholesterol. Intracellular cholesterol (in the cytoplasm) of the liver regulates the gene expression of HMG CoA reductase in the liver. High cholesterol will downregulate the enzyme and low cholesterol will upregulate the enzyme. #cholesterol #biosynthesis #uses #biochemistry #MetabolismMadeEasy
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This podcast explains how **statin medications** effectively lower **cholesterol levels** by interacting with the **liver's natural processes**. Under normal conditions, the liver both **produces cholesterol** and **removes LDL particles** from the bloodstream using specialized receptors. **Statins** work by **blocking a specific enzyme**, which reduces the amount of cholesterol produced within the liver's cells. To compensate for this internal shortage, the liver **increases its production of L
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