The growth rate of the atmospheric abundance of methane (CH 4) reached a record high of 15.4 ppb yr −1 between 2020 and 2022, but the mechanisms driving the accelerated CH 4 growth have so far been ...

Cell-based therapy using satellite stem cells (SSCs) holds tremendous potential for enhancing muscle regeneration. However, conventional isolation methods often yield heterogeneous cell populations ...

Rapid pathogen detection is crucial for effective disease management, particularly in bloodstream infections. Current molecular diagnostics often require nucleic acid preamplification, adding time and ...

Crystallization of the lunar magma ocean yielded a chemically unique liquid residuum named KREEP. This component is expressed as a large patch on the near side of the Moon and a possible smaller patch ...

Heritable microbes can regulate insect reproduction in diverse ways (1). For example, some symbionts which have been called reproductive manipulators, cause cytoplasmic incompatibility, male-killing, ...

Using novel mouse models, we establish cyclin-dependent kinase 12 (CDK12) as a bona fide tumor suppressor gene in tubo-ovarian high-grade serous carcinoma, demonstrating that its loss drives increased ...

Nav1.8 voltage-gated sodium channels are strongly expressed in human primary pain-sensing neurons (nociceptors) and a selective Nav1.8 inhibitor VX-548 (suzetrigine) has shown efficacy for treating ...

In This IssueThe chemical by-products of dimethyl sulfide (DMS), a source of atmospheric sulfur emissions from the ocean, contribute to aerosol formation, influencing cloud formation, albedo, and ...

Turbulence at centimeter scales plays a pivotal role in shaping the overturning circulation of the deep ocean (1, 2), as well as the ocean’s capacity to distribute and store climate-critical tracers ...

Long-term light at night (LAN) exposure poses a health threat to nocturnal lab animals. Whether diurnal animals suffer the same deleterious effect imposed by LAN and how it works are still open ...

Sporting events can bring people together and forge strong loyalties, but the mechanisms behind their social impact remain unclear. Our study reveals that events peripheral to the game, such as the ...

We demonstrate that substitutionally inert octahedral metal complexes, such as the iridium (III) carbene complex (1a), provide a useful source of potent inhibitors for unexplored oncogenic protein ...