In the draft, the Bills focused on defense, selecting CB Max Hairston (first round), DT TJ Sanders (second), Edge Landon Jackson (third), DT Deone Walker (fourth), CB Jordan Hancock (fifth), TE Jackson Hawes (fifth) and cornerback Dorian Strong (sixth ).

The wide receiver position continues to be a hot-button conversation among fans of the Buffalo Bills, especially after the team failed to make a significant investment in the position during the 2025 NFL Draft.

Brandon Beane built his defense in the NFL Draft and went on a sports talk show and ripped the hosts for "b----ing" about his strategy.

Of the nine picks made by the Bills, seven of them came on the defensive side of the ball. Quality stars like Kentucky's Maxwell Hairston and Arkansas' Landon Jackson have bolstered a defense that is looking for the finishing touches to finally beat Patrick Mahomes and the Kansas City Chiefs.