Indiana enters with a 68.4% chance to take care of business on its home floor, according to ESPN’s matchup predictor. The game will be broadcast on the Big Ten Network with Kevin Kuglar handling play-by-play duties alongside Robbie Hummel.

The Indiana Hoosiers seek their fifth straight win when Southern California visits. Here are starting lineups, game prediction and rankings.

Indiana may be without leading scorer Malik Reneau for a second straight full game, but it still has Oumar Ballo, a matchup problem for USC.

USC has been inconsistent in starting Eric Musselman’s first season, while Indiana has played well and can continue playing well in this game at home against the Trojans. It’s time to continue our College Basketball odds series with a USC-Indiana prediction and pick.