The early 1980s custom build, which was played on tour and once owned by Mick Mars, ushered in a watershed moment for Kramer and the guitar industry

Van Halen's guitar will lead Sotheby's upcoming "Rock & Pop" auction on Oct. 24 during the company's Grails Week (Oct. 21-28). The sale will also include memorabilia from Bob Dylan, the Rolling Stones, the Beatles and more. The auction house estimates the guitar will fetch between $2 million and $3 million.

A previous Sotheby’s sale for a guitar owned by Van Halen — that one on display in the band’s “Hot for Teacher” music video — netted $3,932,000 in April 2023.