Emergency care systems (ECS) address a wide range of acute conditions, including emergent conditions from communicable diseases, non-communicable diseases, pregnancy and injury. Together, ECS ...

Introduction Effective strategies to increase pre-exposure prophylaxis (PrEP) uptake and continuation among adolescent girls and young women (AGYW) who engage in sex work or transactional sex are ...

Background Extreme heat exposure is a growing public health concern. In this trial, we tested the impact of a community health worker (CHW) led heat education programme on all-cause mortality, ...

Introduction Postpartum haemorrhage (PPH) remains the leading cause of maternal death. Yet there is a lack of clarity around what research is needed to determine what works and how best to deliver ...

Ensuring prompt and effective case management of malaria remains an ongoing challenge in Zambia, where care is not sought for roughly 40% of febrile children under 5 years of age. To expand access, ...

Introduction While highly effective for reducing the risk of tuberculosis (TB) disease, TB preventive treatment (TPT) is underused among people living with HIV (PWH). We evaluated the effectiveness of ...

COVID-19 is mutating; unknowns about virulent COVID-19 variants can result in devastating effects on pandemic control and management. Scientific evidence on human–pathogen interactions, such as data ...

Introduction Growing evidence supports linkages between climate change and extreme weather events (EWEs) and sexual and reproductive health (SRH) among adults. Yet knowledge gaps persist regarding ...

Introduction Low high-density lipoprotein (HDL) is widely used as a marker of cardiovascular disease risk, although this relationship is not causal and is likely mediated through associations with ...

Objective Risk factors predisposing infants to community-acquired bacterial infections during the first 2 months of life are poorly understood in South Asia. Identifying risk factors for infection ...

Somalia’s humanitarian and development efforts heavily rely on U.S. Agency for International Development’s (USAID’s) US$1.1 billion annual support, addressing health, food security and governance, but ...

Clinical practice guidelines have the potential to improve quality of care through improving decision making and antibiotic prescription. These guidelines are particularly important in areas with ...