If stretched out, human DNA would be about 2 meters long. For this long strand to fit inside the cell nucleus, which is about 0.01 mm in size, it must be tightly folded. DNA wraps around proteins call ...

One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...

Estrogen is known as an important hormone, and it can control many functions by regulating the activity of hundreds of genes.

Researchers created the most detailed maps yet of the genome’s three-dimensional organization using human stem cells and ...

Imagine if our bodies could grow new organs throughout our entire lives. Plants do this constantly, thanks to tiny, powerful ...

A team of researchers has generated one of the most detailed 3D maps of human chromosomes, cataloging over 140,000 DNA looping interactions.

Research reveals that five DNA letters can switch chromatin between fluid and solid-like states, influencing gene ...

The research represents a major step forward in revealing how the three dimensional form of DNA shapes the way human biology functions. In a major step toward understanding how the physical form of ...

A new study shows, for the first time, how the human genome folds and moves in 3D over time to control when genes turn on and ...

The genetic heritage is not a simple, static list inside the cell nucleus. It unfolds into a dynamic architecture whose intimate folds govern the destiny of cells. A mapping of ...