Many promising therapies fail because preclinical models do not fully capture the complexity of the human heart. A new review ...

An AI-assisted drug discovery platform using transfer learning has identified a promising gp130 inhibitor for colorectal ...

Researchers have developed a scalable bioreactor-based system to produce cardiac organoids that successfully integrated into ...

One, an integrated platform combining high-throughput ADME testing with AI-powered human pharmacokinetic projections.

Based Models is calling for greater flexibilty from the FDA to accomodate rapidly changing technologies like stem ...

At AACR 2026, industry leaders discussed how oncology R&D is moving beyond isolated technological advances towards integrated ...

German researchers have used cerebral organoids to investigate how the epilepsy medication valproate interferes with early ...

Researchers have identified metabolic vulnerabilities in Fibrolamellar cancer, a rare liver malignancy affecting adolescents and young adults, using functional profiling and mass spectrometry. The ...

A novel 3D-printed confined culture system has enabled researchers to generate larger, more advanced human gastrointestinal ...

NIH researchers have identified the intracellular signalling pathways through which semaglutide and other GLP-1 receptor agonists induce weight loss, revealing why patient responses vary and treatment ...

Tau tangles are a hallmark of Alzheimer's disease and related disorders, but evidence suggests the real damage may come from ...

Genome-wide association studies have linked thousands of genetic variants to disease, yet most remain disconnected from drug-relevant biology. Neville Sanjana, Professor at New York University and ...