Drugs made of mRNA have the potential to transform medicine—if only they could get into cells in one piece. Now, University ...
How does the cell convert DNA into working proteins? The process of translation can be seen as the decoding of instructions for making proteins, involving mRNA in transcription as well as tRNA. But ...
In a new study, published in Cell, researchers describe a newfound mechanism for creating proteins in a giant DNA virus, comparable to a mechanism in eukaryotic cells. The finding challenges the dogma ...
Researchers shamelessly copy viral strategies to get mRNA medicines into cells in one piece (Illustration courtesy of Joe Luciani ...
Radiation therapy is highly effective at killing cancer cells, but it often harms healthy skin around the treatment area, a common side effect experienced by up to 95% of cancer patients undergoing ...
Researchers identified how the poxvirus protein VITF-3 forms a molecular ring that clamps onto DNA with viral RNA polymerase, ...
N of 1 therapy uniquely developed, on demand, for infant with life-threatening rare metabolic disorder in six months Results published in The New England Journal of Medicine and showcased at American ...
Real-World Plasma Thymidine Kinase Activity in High-Risk and Metastatic Hormone Receptor–Positive, Human Epidermal Growth Factor Receptor 2–Negative Breast Cancer Treated With Cyclin-Dependent Kinase ...
AI can help protein engineers optimize the transcription enzymes used to make mRNA-based vaccines and therapeutics, say the authors of a new study.
Therapeutic mRNA delivered via lipid nanoparticles restored sperm production in genetically infertile mice and produced live ...