Membrane fusion and budding mediate fundamental biological processes like intracellular trafficking, exocytosis, and endocytosis. For many decades, fusion has been thought to open a nanometer-range ...
Researchers at UNC Lineberger Comprehensive Cancer Center and colleagues have determined that a specific type of immune cell—type II innate lymphoid cells (ILC2s)—can change its characteristics and ...
PSA as a predictor of small cell transformation in prostatic adenocarcinoma: A SEER 2000-2021 study.
Global burden of prostate cancer in 38 OECD countries and its trend from 1990-2021: An Insight from the Global Burden of Disease study 2021. This is an ASCO Meeting Abstract from the 2025 ASCO Annual ...
In this JCO Article Insights episode, Alexandra Rojek provides a summary on "Anti-CD19 Chimeric Antigen Receptor T-cell therapy for Richter’s Transformation: An International, Multicenter, ...
There is a challenge related to prostate and many other cancers that cancer cells form resistance to treatments as the disease progresses. However, these resistance mechanisms are not yet fully ...
CD19-targeted CAR T-cell therapy shows a 65% response rate in Richter transformation, with median progression-free survival of 8 months and overall survival of 14.4 months. Early response and age are ...
Researchers have determined that type II innate lymphoid cells (ILC2s), a type of immune cell, can change its characteristics and functions after a cancer patient receives stem cells from a donor, ...
The image shows prostate cancer cells in which KLF4 (red) and the CD44 protein (green) on the cell membrane are stained. There is a challenge related to prostate and many other cancers that cancer ...
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