The Noelin family of secreted proteins bind to the external portion of AMPA glutamate receptors and stabilize them on the neuronal cellular membrane, a process necessary for transmission of ...
Biophysicists from the Moscow Institute of Physics and Technology and the University of Groningen in the Netherlands have visualized a nearly complete transport cycle of the mammalian glutamate ...
An analysis of how synaptic proteins change during early development reveals differences between mice and marmosets but also what's different in individuals with autism spectrum disorders. The ...
The brain has the ability to modify the contacts between neurons. Among other things, that is how it prevents brain activity from getting out of control. Researchers have now identified a mechanism ...
A team of UK researchers has, for the first time in living human brains, demonstrated how the cognitive dysfunction seen in schizophrenia may be caused by the lack of a key protein known to facilitate ...
The human brain contains nearly 86 billion neurons, constantly exchanging messages like an immense social media network, but neurons do not work alone – glial cells, neurotransmitters, receptors, and ...
What makes synapses disappear with age? In the January 21 Nature, scientists led by Tony Wyss-Coray at Stanford University School of Medicine, California, report that sluggish turnover of synaptic ...
The image taken at the CFcryo-EM (Core Facility for cryo-Electron Microscopy) captures the moment during which a vesicle (arrow) fuses with the cell membrane. By superimposing several electron ...