The Lions, Bills and Eagles form a top tier in odds to win the Super Bowl with the Chiefs out of the top two for the first time this season.

Heading into Week 16, the Buffalo Bills are betting favorites (+425) to win the Super Bowl. Josh Allen is also the MVP favorite.

The Los Angeles Rams are finally healthy, and the results are starting to come. After a big win vs. Buffalo, their Super Bowl odds are on the move. Join Chris Vasile as he breaks down the biggest risers and fallers ahead of Week 16.

The Buffalo Bills won a potential Super Bowl preview against the Detroit Lions, the Tampa Bay Buccaneers raised eyebrows with their dominant 40-17 victory over the Los Angeles Chargers and the Philadelphia Eagles won the "Pennsylvania Bowl" vs.

The Buffalo Bills, fresh off of their spectacular 48-42 victory over the Detroit Lions, have earned the best betting odds to make the Super Bowl. Not just the best odds in the AFC. Buffalo has the best odds in the NFL.

Super Bowl betting odds are on the move! While the Lions are still the favorites, the Chiefs and Bills saw their odds shift after Week 14.

Allen is playing the best football of his career, with 36 combined touchdowns and only seven turnovers for the AFC East champions.