The stroma to tumor ratio potentially identifies higher risk bladder cancer tumors and might help guide immunotherapy. Bladder tumors with higher stromal content may have a more immunosuppressive ...

Researchers at the University of Pittsburgh have identified a novel trigger of a deadly form of ovarian cancer. Discovery of a subset of high-risk progenitor cells that reside in fallopian tube ...

The tumour–stroma ratio (TSR) is emerging as a robust, cost‐effective histopathological parameter that quantifies the relative proportion of neoplastic cells to the surrounding stromal tissue.

—In this study, molecular classification of endometrial cancer with cervical stromal invasion was associated with recurrence-free survival by univariate analysis. But after controlling for tumor stage ...

She identified 2 primary frontiers for clinical investigation: the eradication of persistent cancer cells and the management ...

The optimal duration of adjuvant imatinib has yet to be determined, and clinical trials are ongoing to address this. KIT-directed tyrosine kinase inhibitors (TKIs) are the key treatment for advanced ...

A real-world study of claudin 18.2 (CLDN18.2) association with molecular subtypes, mutations/biomarkers, immune landscapes, and gene signatures and prognostic value in pancreatic ductal adenocarcinoma ...

MTX240's mechanistic novelty may give it a long-awaited edge in treatments for gastrointestinal stromal tumors (GIST) ...

GISTs originate from interstitial cells of Cajal and are staged by size, location, mitotic rate, and genetic mutations, influencing treatment strategies. Diagnosis involves imaging, endoscopy, biopsy, ...