Researchers used CRISPR gene editing to selectively kill cancer cells with amplified oncogenes. In animal and cellular models ...

The onset and aggressiveness of cancer are related to the abnormal behavior of certain genes, known as oncogenes. The best-known of these alterations is mutation, but it is not the only one. Sometimes ...

In cellular and animal models of neuroblastoma, small cell lung cancer and colon cancer, this strategy reduces tumours, prolongs survival and triggers a tumour-fighting immune response. The study, ...

KRAS is the most frequently mutated oncogene across all human cancers. Although different KRAS mutations have long been thought to exert the same cancer-driving effects, a new study led by UT ...

Colorectal cancer (CRC) is a leading cause of cancer deaths worldwide, and only around 10% of patients survive for five years after being diagnosed. In a study, published in the journal Gut, a ...

Lung cancer in never smokers is rising, with distinct risks and biology, highlighting the need for tailored screening, ...

However, several targeted therapies have recently been developed for potentially actionable alterations, including BRAF and human epidermal growth factor receptor 2 (HER2) oncogenes, advancing the ...

Scientists at the UVA Comprehensive Cancer Center say they have found a small molecule that can shut down a gene tied to glioblastoma, a discovery that could eventually point to a new way to treat ...

Spanish actor Antonio Banderas has announced that he will financially support the work of renowned bio-chemist Dr Mariano ...

Perioperative therapy has become a critical component in the management of resectable non–small cell lung cancer (NSCLC), particularly in the era of precision medicine. Although molecular testing is ...