Until recently, Markov models and analytical methods were fairly obscure mathematical techniques rarely applied outside of academic settings. The advent of functional safety standards, particularly ...
Representative structures for each of the four metastable states identified by our Markov State Model (MSM; S1-S4) and connected by the top one pathway from the pre-translocation state (S1) to the ...
The dynamics of the RNA polymerase II (Pol II) backtracking process is poorly understood. Scientists have now built a Markov State Model from extensive molecular dynamics simulations to identify ...
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