Immunoglobulins are central to shaping immune responses and are critical tools for probing biological mechanisms in biomedical research. However, selecting an inappropriate antibody isotype can lead ...
In a recent medRxiv* preprint paper, researchers from Mount Sinai in New York showed that all three major immunoglobulin isotypes (IgM, IgG, and IgA) produced by our immune cells were capable of ...
The 2020 pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continues to rage. While PCR-based assays are used for viral diagnosis, high through-put, rapid serologic ...
In a recent study posted to the medRxiv* preprint server, researchers reported a class switch in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-specific antibodies due to repeated ...
Immunoglobulin isotypes that poorly activate effector mechanisms that protect the host against pathogens can induce anti-inflammatory effects and protect against immune-complex-dependent renal disease ...
Type 1 diabetes is perceived as a chronic autoimmune disease that is thought to result from T cell-mediated destruction of the insulin-producing pancreatic β cells (1). During an asymptomatic ...
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