Study found that EPAC2 levels appear to rise gradually as the brain matures, suggesting it may have particular relevance as a ...

UCLA Health researchers have identified a potential drug target for treating Fragile X syndrome, the most common genetic ...

Blocking the brain protein EPAC2 reverses sensory hypersensitivity, social deficits, and seizures in Fragile X syndrome.

Fragile X Syndrome: Symptoms, Diagnosis, Treatments and Complications: By Shreoshree Chakrabarty Fragile X Syndrome (FXS), also known as FX syndrome or fragile syndrome, is the most common inherited ...

Mutations in FMR1, the gene encoding fragile X messenger ribonucleoprotein 1 (FMRP), located at Xq27.3 and discovered in 1991, are the leading single-gene causes of autism and intellectual disability.

A new study shows that enhancing activity of a specific component of 'NMDA' receptors normalizes protein synthesis, neural activity and seizure susceptibility in the hippocampus of fragile X lab mice.

According to the Cleveland Clinic, Fragile X syndrome is the most common inherited cause of intellectual disability ...