Every now and then, we come across a custom bike whose story is just as interesting as the mods carried out. This is one such ...

I have to admit, going through scores of customized Harley-Davidson motorcycles is a delight. Not only am I treated to incredible base machines, but I get to see them in the most diverse and ...

A lot of Harley Davidson models are also known by their FXR designations. What do those actually mean? Why are the model names used instead?

Farnesoid X receptor (FXR) has important roles in maintaining bile acid and cholesterol homeostasis. Here we report that the antiparasitic drug ivermectin is a ligand for nuclear FXR. We identify ...

Harley-Davidson has had some impressive bikes in its catalog in its century-long run. The motorcycle manufacturer has some of the most successful motorcycles in history, from the Softail Fat-Boy and ...

The systemic expression of the bile acid (BA) sensor farnesoid X receptor (FXR) has led to promising new therapies targeting cholesterol metabolism, triglyceride production, hepatic steatosis and ...

Eli Lilly has acquired Organovo’s lead asset, a clinical FXR agonist designed to treat inflammatory bowel disease (IBD), in a deal worth up to $50 million in biobucks. Organovo’s stock skyrocketed 244 ...

The farnesoid X receptor (FXR) is a bile acid nuclear receptor that plays a crucial role in regulating bile acid and sterol metabolism. Bile acids are natural ligands of FXR, which bind to the ...

FXR selects Industrials stocks from the Russell 1000 Index with high growth or value scores, whichever is better. Its expense ratio is 0.60% and FXR has $1.97 billion in assets. Its tiered-weighting ...

The pleiotropic actions of the Farnesoid X Receptor (FXR) are required for gut health, and reciprocally, reduced intestinal FXR signaling is seen in inflammatory bowel diseases (IBDs). Here, we show ...