In this rapidly evolving setting, clinicians are weighing the alleged harm of continuing these medications in patients for whom ACE inhibitors and ARBs have known benefit against the harm to their ...

AbstractPulmonary arterial hypertension (PAH) is associated with aberrant pulmonary vascular remodeling that leads to increased pulmonary artery pressure, pulmonary vascular resistance, and right ...

Global trends predict a steady rise in cardiovascular disease in the next decade, and by 2020 coronary heart disease is predicted to be the leading cause of death worldwide. 1 Although lifestyle is ...

Medically reviewed by Jeffrey S. Lander, MD Key Takeaways Obesity can increase the heart's workload, leading to high blood ...

The renin-angiotensin system (RAS) is a major regulatory system that has both cardiovascular and renal functions. RAS activation results in elevated concentrations of angiotensin-II (the principal ...

Utility of the Breast Cancer Index (BCI) in the clinical practice. CD205, a target antigen for a novel ADC: Evaluation of antigen expression on TNBC, pancreatic adenocarcinoma and bladder urothelial ...

An aldosterone antagonist (AA) should be the drug of choice when adding a second renin-angiotensin-aldosterone system (RAAS) blocker to ACE inhibitors in patients with symptomatic systolic HF despite ...

In a recent study posted to the medRxiv* preprint server, researchers conducted an umbrella review and meta-analysis of the renin-angiotensin-aldosterone system (RAAS) inhibitors' impact on ...

A recent study posted to the medRxiv* preprint server investigated the association of renin-angiotensin-aldosterone system (RAAS)-mediated hypertension (HT) with coronavirus disease 2019 (COVID-19).

Studies in animals have shown that ACE2 is used by coronaviruses as a functional receptor. ARBs and ACE inhibitors increase the expression of ACE2; a hypothesis that their use may modify ...