Wayland is a city in Clark County, Missouri, United States. As of the 2020 census, its population was 408. It is part of the Fort Madison–Keokuk…Wayland is a city in Clark County, Missouri, United States. As of the 2020 census, its population was 408. It is part of the Fort Madison–Keokuk, IA-MO Micropolitan Statistical Area. Wayland was laid out in 1880. The city was named for Jerre Wayland, a pioneer settler. A post office called Wayland has been in operation since 1874.